A third dose of the Pfizer/BioNTech Covid-19 vaccine can "strongly" boost protection against the Delta variant -- beyond the protection afforded by the standard two doses, suggests new data released by Pfizer on Wednesday. From a report: The data posted online suggest that antibody levels against the Delta variant in people ages 18 to 55 who receive a third dose of vaccine are greater than fivefold than following a second dose. Among people ages 65 to 85, the Pfizer data suggest that antibody levels against the Delta variant after receiving a third dose of vaccine are greater than 11-fold than following a second dose. The data, which included 23 people, have not yet been peer-reviewed or published. During a company earnings call on Wednesday morning, Dr. Mikael Dolsten, who leads worldwide research, development and medical for Pfizer, called the new data on a third dose of vaccine "encouraging." "Receiving a third dose more than six months after vaccination, when protection may be beginning to wane, was estimated to potentially boost the neutralizing antibody titers in participants in this study to up to 100 times higher post-dose three compared to pre-dose three," Dolsten said in prepared remarks. "These preliminary data are very encouraging as Delta continues to spread." The data also show that antibody levels are much higher against the original coronavirus variant and the Beta variant, first identified in South Africa, after a third dose.

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I heard from a friend of Gary Sevitsky, a colleague of mine in the late 70s at the University of Wisconsin. He and I were both smokers and grad students in Computer Science, so we'd go out for smoking breaks together while working at the Unix lab on West Dayton St. It was in one of our hallway smoking conversations that he told me about Lisp editors that understood structure. I loved the idea, but I was programming in C, so I decided to build an editor for that language, with the same idea. That started me down a path that to this day I'm still working on. The combination of outline structures and programming, it's a big deal. I never spoke with him after leaving Madison, and after the Guy Kawasaki podcast I heard from a friend of his who said that Gary had died at age 57, in 2013. He was a kind, brilliant man, and a friend from one of the best times of my life.

In the future, kids will learn about the attempt to overthrow the government that failed, but they let the coup leaders stay in Congress and they tried again, and again, and again. Kids of the future will wonder why the people of America didn't force the politicians to evict the terrorists. Instead, it took 20 years to get them out of the government, in the meantime the planet became unlivable, billions died and civilization basically dissolved. Right now that's the story that should be being reported in the news. Wait longer, the story gets worse.

The PlayStation 5 just crossed a significant milestone. Sony has revealed that it has sold 10 million PS5 consoles as of July 18th, eight months after the system's November 12th debut. From a report: The company considered that no mean feat between the pandemic and ongoing chip shortages that reportedly held sales back. It's now Sony's fastest-selling console to date, outpacing the PS4 by nearly a month. Sales have slowed down since launch. Sony racked up 4.5 million PS5 sales in 2020, but sold 3.3 million in the first quarter of 2021 -- it took another four months to add 2.2 million to the tally. That's not surprising between supply constraints and the usual mid-year slump, but you might not see sales climb until the holidays. PlayStation chief Jim Ryan told GamesIndustry.biz in an interview that it was "too early to tell" which markets were the hottest given widespread demand, but pointed out that China was a pleasant surprise. The company sold out its PS5 launch stock "very, very quickly" despite a local market focused on mobile games and the free-to-play model.

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Israeli government officials visited the offices of the hacking company NSO Group on Wednesday to investigate allegations that the firm's spyware has been used to target activists, politicians, business executives, and journalists, the country's Ministry of Defense said in a statement today. From a report: An investigation published last week by 17 global media organizations, claims that phone numbers belonging to notable figures have been targeted by Pegasus, the notorious spyware that is NSO's best-selling product. The Israeli Ministry of Defense did not specify which government agencies were involved in the investigation, but Israeli media previously reported that the Foreign Ministry, Justice Ministry, Mossad, and Military Intelligence were also looking into the company following the publication of the Pegasus Project. NSO Group CEO Shalev Hulio confirmed to MIT Technology Review that the visit had taken place, but continued the company's denials that the list published by reporters was linked to Pegasus. "That's true," he said. "I believe it's very good that they are checking, since we know the truth and we know that the list never existed and is not related to NSO." The reports focused largely on the successful hacking of 37 smartphones of business leaders, journalists, and human rights activists. But they also pointed to a leaked list of over 50,000 more phone numbers of interest in countries that are reportedly clients of NSO Group. The company has repeatedly denied the reporting. At this point, both the source of and meaning of the list remain unclear, but numerous phones on the list were hacked according to technical analysis by Amnesty International's Security Lab. When asked if the government's investigation process will continue, Hulio said he hopes it will be ongoing. "We want them to check everything and make sure that the allegations are wrong," he added.

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Walmart's investments in software and retail technologies it used to transform its business from a brick-and-mortar to one that combines both in-person and online shopping will now be made available to other retailers for the first time, the company announced today. From a report: Through a strategic partnership with Adobe, Walmart will integrate access to Walmart's Marketplace, as well as its various online and in-store fulfillment and pickup technologies, into the Adobe Commerce Platform. The technologies will be made available to both Adobe Commerce and Magento Open Source customers, Adobe says. The deal will allow Walmart to potentially reach thousands of small to mid-sized retailers, who will effectively be able to tap into the same tools that one of the largest global retailers is using to run their business. Through the partnership, Adobe retail customers will be able to do things like show store pickup eligibility and available pickup times online; offer multiple pickup options like curbside and in-store pickup; provide their store associates with mobile tools to pick for orders, validate item selections and handle substitutions; and use tools to communicate with customers about their pickup orders, like those where customers can alert store associates of their ETA or arrival for curbside pickup. Another aspect of the partnership will allow retailers to syndicate and sell their products across Walmart's Marketplace.

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The White House is signaling to U.S. critical infrastructure companies, such as energy providers that they must improve their cyber defenses because additional potential regulation is on the horizon. From a report: U.S. President Joseph Biden signed a national security memorandum on Wednesday, launching a new public-private initiative that creates "performance controls" for cybersecurity at America's most critical companies, including water treatment and electrical power plants. The recommendations are voluntary in nature, but the administration hopes it will cause companies to improve their cybersecurity ahead of other policy efforts, said a senior administration official. The announcement comes after multiple high profile cyberattacks this year crippled American companies and government agencies, including a ransomware incident which disrupted gasoline supplies. "These are the thresholds that we expect responsible owners and operators to go," said the official. "The absence of mandated cybersecurity requirements for critical infrastructure is what in many ways has brought us to the level of vulnerability that we have today."

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The U.S. economy stands to gain $160 billion a year in extra output from a successful national high-speed internet plan that would boost labor productivity and allow more people to work from home, according to new research. From a report: The study, which is based on survey data, attempts to put precise numbers on one of the bigger unknowns in President Joe Biden's infrastructure plan: how much is universal broadband really worth? "Moving to high-quality, fully reliable home internet service for all Americans would raise earnings-weighted labor productivity by an estimated 1.1% in the coming years," economists Jose Maria Barrero, Nicholas Bloom and Steven Davis wrote in a paper released July 27. "The implied output gains are $160 billion per year," equivalent to about 0.7% of gross domestic product. The study's authors describe an "abrupt, enormous" shift to remote work as a result of the pandemic, which they expect to settle with about 20% of the U.S. labor force persistently working from home. The share could be higher for so-called knowledge workers whose jobs are mostly done on computer networks anyway.

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Thousands of scientists have repeated calls for urgent action to tackle the climate emergency, warning that several tipping points are now imminent. From a report: The researchers, part of a group of more than 14,000 scientists who have signed on to an initiative declaring a worldwide climate emergency, said in an article published in the journal BioScience on Wednesday that governments had consistently failed to address "the overexploitation of the Earth," which they described as the root cause of the crisis. Since a similar assessment in 2019, they noted an "unprecedented surge" in climate-related disasters, including flooding in South America and Southeast Asia, record-shattering heatwaves and wildfires in Australia and the US, and devastating cyclones in Africa and South Asia. For the study, scientists relied on "vital signs" to measure the health of the planet, including deforestation, greenhouse gas emissions, glacier thickness and sea-ice extent and deforestation. Out of 31 signs, they found that 18 hit record highs or lows. For example, despite a dip in pollution linked to the COVID-19 pandemic, levels of atmospheric CO2 and methane hit all-time highs in 2021. Greenland and Antarctica recently showed all-time low levels of ice mass and glaciers are melting 31-percent faster than they did just 15 years ago, the authors said. Ocean heat and global sea levels set new records since 2019, and the annual loss rate of the Brazilian Amazon reached a 12-year high in 2020. Echoing previous research, the researchers said forest degradation linked to fire, drought and logging was causing parts of the Brazilian Amazon to now act as a source of carbon, rather than absorb the gas from the atmosphere.

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Two U.S. senators on Wednesday said they are introducing a measure to prohibit funds in a $1.9 trillion government funding measure from being used to purchase Chinese telecommunications equipment from Huawei and ZTE and others deemed U.S. security threats. From a report: Senators Tom Cotton, a Republican, and Mark Warner, a Democrat, said the funds that were approved in March in a law known as the American Rescue Plan should not be used to potentially undermine U.S. telecommunications networks.

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Portrait of Luther Burbank, 1931.

On the Ashokan Rail Trail yesterday.

Five public research institutions in France have imposed a 3-month moratorium on the study of prions -- a class of misfolding, infectious proteins that cause fatal brain diseases -- after a retired lab worker who handled prions in the past was diagnosed with Creutzfeldt-Jakob disease (CJD), the most common prion disease in humans. From a report: An investigation is underway to find out whether the patient, who worked at a lab run by the National Research Institute for Agriculture, Food and Environment (INRAE), contracted the disease on the job. If so, it would be the second such case in France in the past few years. In June 2019, an INRAE lab worker named Emilie Jaumain died at age 33, 10 years after pricking her thumb during an experiment with prion-infected mice. Her family is now suing INRAE for manslaughter and endangering life; her illness had already led to tightened safety measures at French prion labs.

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The big bug in our system is that the world is run mostly by people who are playing it safe.

If you're a PagePark user, here's a potential security issue I want to fix, but there is breakage, that's why I wanted to check with users first.