schwit1 shares a report from France 24: NASA has announced the first crewed flight by a SpaceX rocket to the International Space Station (ISS) is expected to take place in June 2019. It will be the first manned U.S. launch to the orbiting research laboratory since the space shuttle program was retired in 2011, forcing U.S. astronauts to hitch costly rides aboard Russian Soyuz spacecraft. A flight on Boeing spacecraft is set to follow in August 2019. The timetable for both launches has already been postponed several times, but NASA said Thursday it would now be providing monthly updates on deadlines. Both missions are considered tests: the two astronauts transported in each flight will spend two weeks aboard the orbiting ISS before returning to Earth. SpaceX will carry out an uncrewed test in January 2019, and Boeing in March 2019.

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Data from the national election bureau shows that only 20.4 percent of Romanians voted in the referendum.

Muslim Russian fighter leaps into McGregor's corner and sparks scuffles after retaining lightweight title in Las Vegas.

An anonymous reader quotes a report from The Guardian: In a lab just south of San Francisco I am looking at two blown-up images of microscope slides on a computer screen, side by side. The slides are the same cross-sections of mouse knees from a six-month-old and an 18-month-old animal. The older mouse's image has a splattering of little yellow dots, the younger barely any. That staining indicates the presence of so-called senescent cells -- "zombie cells" that are damaged and that, as a defense against cancer, have ceased to divide but are also resistant to dying. They are known to accumulate with age, as the immune system can no longer clear them, and as a result of exposure to cell-damaging agents such as radiation and chemotherapy. And they have been identified as a cause of aging in mice, at least partially responsible for most age-related diseases. Seeing the slides, it makes me worried about my own knees. "Tell us about it," says Pedro Beltran who heads the biology department at Unity Biotechnology, a 90 person-strong company trying to halt, slow or reverse age-associated diseases in humans by killing senescent cells. Developing therapies to kill senescent cells is a burgeoning part of the wider quest to defeat aging and keep people healthier longer. Unity, which was founded in 2011, has received more than $385m in funding to date including investment from big tech names such as Amazon's Jeff Bezos and PayPal co-founder Peter Thiel. It went public this May and is valued at more than $700m. Its first drug entered early clinical trials in June, aimed at treating osteoarthritis. Other startups with zombie cells in their sights include Seattle-based Oisin Biotechnologies which was founded in 2016 and has raised around $4m; Senolytic Therapeutics whose scientific development is based in Spain and which was established last September (it won't disclose its financing other than to say it has a first round, which will allow it to reach clinical trials); and Cleara Biotech, formed this June backed by $3m in funding and based in the Netherlands. In addition, Scottish company CellAge, also founded in 2016, has raised about $100,000 to date, partly through a crowdfunding campaign. The report goes on to detail Unity's plan to kill senescent cells. Their method is to target the biological pathways senescent cells use to resist the normal death of aging cells. "The company's approach is to find small molecules (so called 'senolytics') that can do this," reports The Guardian. "But because small molecules, by their nature, can get everywhere in the body, the approach is prone to unwanted side-effects." As a result, the company has turned to localized treatment. Meanwhile, Oisin is trying to kill all a person's zombie cells in one go. "The idea is to load the body with nanoparticles that insert a 'suicide gene' into every cell," reports The Guardian. "It only triggers if a cell has a lot of particular protein (p16) that acts as a marker of zombie cells, albeit imperfectly." It plans to test this method on late-stage cancer patients next year.

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After it was reported that proprietary diagnostic software was needed in order to replace key parts on computers equipped with Apple's T2 chip, iFixit decided to put that claim to the test by replacing a part on a brand-new 2018 MacBook Pro. They found that after pulling it apart and replacing the display, it still worked -- even without the software. Engadget reports: As they put it, any "secret repair kill switch hasn't been activated -- yet." So far, it has limited approaches that limit repairs based on security to the TouchID and FaceID sensors that require specialized software, as I noted yesterday, even though people have reported trouble with the ambient light sensor after replacing iPhone displays. While it's possible that a future software update could change things and make it require specialized software that only official Apple Stores and authorized service centers have access to, we're not there yet. Passing "right to repair" laws currently under consideration could be a big step to guaranteeing things stay that way.

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The ruling Gabonese Democratic Party has won 80 of the 143 seats in the national parliament, the presidency says.

US President Donald Trump's anti-immigration policies are pushing more minorities to promote a shift in the state's political landscape.

The body of 30-year-old Viktoria Marinova was found in a park, showing signs of blows to the head and suffocation.

After ongoing discussions and proposals about new taxes and fees to compensate creators for "missed revenue," the Screen Composers Guild of Canada is calling for a copyright tax on all broadband data use above 15 gigabytes per month. TorrentFreak reports: A proposal from the Screen Composers Guild of Canada (SCGC), put forward during last week's Government hearings, suggests to simply add a levy on Internet use above 15 gigabytes per month. The music composers argue that this is warranted because composers miss out on public performance royalties. One of the reasons for this is that online streaming services are not paying as much as terrestrial broadcasters. The composers SCGC represents are not the big music stars. They are the people who write music for TV-shows and other broadcasts. Increasingly these are also shown on streaming services where the compensation is, apparently, much lower. SCGC's solution to this problem is to make every Canadian pay an extra fee when they use over 15 gigabytes of data per month. This money would then be used to compensate composers and fix the so-called "value gap." As a result, all Internet users who go over the cap will have to pay more. Even those who don't watch any of the programs where the music is used. However, SCGC doesn't see the problem and believes that 15 gigabytes are enough. People who want to avoid paying can still use email and share photos, they argue. Those who go over the cap are likely streaming not properly compensated videos. SCGC writes: "[W]hen you're downloading and consuming over 15 gigabytes of data a month, you're likely streaming Spotify. You're likely streaming YouTube. You're likely streaming Netflix. So we think because the FANG companies will not give us access to the numbers that they have, we have to apply a broad-based levy. They're forcing us to."

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Vehicle was carrying a party on their way to a wedding reception in Schoharie County near Albany, witness says.

Pompeo and Kim 'refine options' for the location and date of a second summit between North Korean leader and Trump.

An anonymous reader quotes a report from Reuters: Britain's national cyber security agency said on Friday it had no reason to doubt the assessments made by Apple and Amazon challenging a Bloomberg report that their systems contained malicious computer chips inserted by Chinese intelligence services. "We are aware of the media reports but at this stage have no reason to doubt the detailed assessments made by AWS and Apple," said the National Cyber Security Centre, a unit of Britain's eavesdropping agency, GCHQ. AWS refers to Amazon Web Services, the company's cloud-computing unit. "The NCSC engages confidentially with security researchers and urges anybody with credible intelligence about these reports to contact us," it said. Apple's recently retired general counsel, Bruce Sewell, told Reuters he called the FBI's then-general counsel James Baker last year after being told by Bloomberg of an open investigation into Super Micro Computer, a hardware maker whose products Bloomberg said were implanted with malicious Chinese chips. "I got on the phone with him personally and said, 'Do you know anything about this?," Sewell said of his conversation with Baker. "He said, 'I've never heard of this, but give me 24 hours to make sure.' He called me back 24 hours later and said 'Nobody here knows what this story is about.'" The U.S. Department of Homeland Security said on Saturday that it too had no reason to doubt statements from companies that have denied the Bloomberg report. "The Department of Homeland Security is aware of the media reports of a technology supply chain compromise," DHS said in a statement. "Like our partners in the UK, the National Cyber Security Center, at this time we have no reason to doubt the statements from the companies named in the story," it said.

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Sanitation systems were destroyed by the earthquake and tsunami that struck Sulawesi Island and leading to rising concern about a disease epidemic in the aftermath.

'Today, we received an extraordinary message: a witness has found a mini-lion in a cage,' police wrote on Facebook.

Authorities speak out days after Meng Hongwei vanished during his trip to Beijing, saying he is under investigation.